2011年-2015年CFDA新藥臨床試驗(yàn)信息   [更多]

文獻(xiàn)名稱： 1、Bagdasarova,A.V.,Vestnik Oftalmologii,1969;2:43-45 2、Powell J. C. et al. Heparin inhibits mammalian but not leech hyaluronidase. Thromb. Res. 1989,55: 791-796 3、Powell J. C. et al. 1989 The spreading activity of leech hyaluronidase makes it a potential drug delivery agent . British Connective Tissue Society meeting. Cardiff, April 1989.   [更多]

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藥智網(wǎng)建有一個(gè)中標(biāo)數(shù)據(jù)庫http://db.yaozh.com/yaopinzhongbiao.html收集了全國各省市的藥品中標(biāo)信息，為了保證給大家有更準(zhǔn)確及時(shí)的信息，需要對(duì)藥品中標(biāo)信息數(shù)據(jù)庫及時(shí)更新，現(xiàn)請(qǐng)人進(jìn)行最新中標(biāo)數(shù)據(jù)的收集整理。 工作內(nèi)容：及時(shí)查到最新公布的藥品中標(biāo)信息，并將最新的文件按指定要求處理成規(guī)范的格式(excel表)。 不是一次性任務(wù)。長期合作(一年以上)   [更多]

需求文獻(xiàn)： 1、DAWSON PA， KARPEN SJ． Bile acids reach out to the spinal cord： new insights to the pathogenesis of itch and analgesia in cholestatic liver disease ［J］． Hepatology， 2014， 59 （4）：1638－1641． 2、Kremer AE, van Dijk R, Leckie P, et al. Serum autotaxin is increased in pruirtus of cholestasis, but not of other oirgin, and responds to therapeutic interventions[J]. Hepatology, 2012(56): 1391-1400. 3、Long-term clinical impact and cost-effectiveness of obeticholic acid for the treatment of primary biliary cholangitis. Sumeyye Samur,Matthew Klebanoff,Reiner Banken,Daniel S. Pratt. 《Hepatology》 , 2017 , 65 (3) :920. 4、Obeticholic acid for PBC. Hugh Thomas. Nature Reviews Gastroenterology & Hepatology 13, 558-559 (2016). 5、Emerging and future therapies for nonalcoholic steatohepatitis in adults. Gesthimani Mintziori , Stergios A. Polyzos. 《Expert Opinion on Pharmacotherapy》 , 2016 , 17 (14) :1 -10. 6、9、Obeticholic acid for the treatment of primary biliary cirrhosis. Trivedi PJ, Hirschfield GM, Gershwin ME. Expert Rev Clin Pharmacol. 2016;9(1):13-26. doi:10.1586/17512433.2015.1092381. Epub 2015 Nov 7. 7、Kowdley K，Nevens F，Andreone P，et al． The first new trials for primary biliary cirrhosis in a decade: an international program evaluating the farnesoid X receptor agonist obeticholic acid［J］． Gastroenterology，2015，1481 ( 4) : S991-S992． 8、Treatment of Non-Alcoholic Fatty Liver Disease . Scherer A., Dufour J.-F. 9、Effects of obeticholic acid on lipoprotein metabolism in healthy volunteers. Pencek R, Marmon T, Roth JD, Liberman A, Hooshmand-Rad R, Young MA. Diabetes Obes Metab. 2016 Sep;18 (9):936-40. doi: 10.1111/dom.12681. Epub 2016 Jun 6. 10、Metabolite profiling of CHO?cells with different growth characteristic 11、Sun, Zhaoyun; Peng, Xinhua; Dong, Xiongzi; Shi, Wenwen - Asian Journal of Chemistry, 2012, vol. 24, # 2, p. 929 - 930 要求：下載符合需求的文獻(xiàn)PDF格式打包上傳   [更多]

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文獻(xiàn)名稱： 1、 A randomized controlled trial of pimecrolimus cream 1% in adolescents and adults with head and neck atopic dermatitis and intolerant of, or dependent on, topical corticosteroids。British journal of Dermatology. Volume 157, Issue 5 November 2007 Pages 954-959 2、Tacrolimus ointment is more effective than pimecrolimus cream with a similar safety profile in the treatment of atopic dermatitis: Results from 3 randomized, comparative studies. JAAD. May 2005Volume 52, Issue 5, Pages 810-822 3、Evaluation of cancer risk related to atopic dermatitis and use of topical calcineurin inhibitors. BJD Volume 165, Issue 3 September 2011 Pages 465-473 4、 Comparative Effectiveness of Topical Calcineurin Inhibitors in Adult Patients with Atopic Dermatitis . American Journal of Clinical Dermatology.April 2012, Volume 13, Issue 2, pp 113-123 5、Alikani M, Fauser BCJ, García-Valesco JA, Simpson JL, Johnson MH. Response from the Editors: first birth following spindle transfer. Reprod Biomed Online. 2017 Jul 20. pii: S1472-6483(17)30308-5. doi: 10.1016/j.rbmo.2017.07.002. [Epub ahead of print] PubMed PMID: 28781009. 6、Alikani M, Fauser BCJ, García-Valesco JA, Simpson JL, Johnson MH. First birth following spindle transfer for mitochondrial replacement therapy: hope and trepidation. Reprod Biomed Online. 2017 Apr;34(4):333-336. doi: 10.1016/j.rbmo.2017.02.004. PubMed PMID: 28385333. 7、 Simpson JL. Reproducing genetics. Genet Med. 2015 Jun;17(6):512-4. doi: 10.1038/gim.2015.37. PubMed PMID: 26035802. 8、Wou K, Feinberg JL, Wapner RJ, Simpson JL. Cell-free DNA versus intact fetal cells for prenatal genetic diagnostics: what does the future hold? Expert Rev Mol Diagn. 2015;15(8):989-98. doi: 10.1586/14737159.2015.1051529. Epub 2015 May 31. Review. PubMed PMID: 26027684. 9、Zhao S, Li G, Dalgleish R, Vujovic S, Jiao X, Li J, Simpson JL, Qin Y, Ivanisevic M, Ivovic M, Tancic M, Al-Azzawi F, Chen ZJ. Transcription factor SOHLH1 potentially associated with   [更多]

文獻(xiàn)名稱: 1、 Premedication with?Intravenous Ibuprofen?Improves Recovery Characteristics and Stress Response in Adults Undergoing Laparoscopic Cholecystectomy: A Randomized Controlled Trial. Le V, Kurnutala L, SchianodiCola J, Ahmed K, Yarmush J, Daniel Eloy J, Shapiro M, Haile M, Bekker A. Pain Med. 2016 Feb 18. pii: pnv113. [Epub ahead of print] 2、 A multicenter, randomized, double-blind placebo-controlled, single dose trial of the safety and efficacy of?intravenous ibuprofen?for treatment of pain in pediatric patients undergoing tonsillectomy. Moss JR, Watcha MF, Bendel LP, McCarthy DL, Witham SL, Glover CD. Paediatr Anaesth. 2014 May;24(5):483-9. doi: 10.1111/pan.12381. Epub 2014 Mar 20. 3、 Early?intravenous ibuprofen?decreases narcotic requirement and length of stay after traumatic rib fracture. Bayouth L, Safcsak K, Cheatham ML, Smith CP, Birrer KL, Promes JT. Am Surg. 2013 Nov;79(11):1207-12. 4、 Impact of oral versus?intravenous ibuprofen?on neurodevelopmental outcome: a randomized controlled parallel study. 5、 Ahn BO, Dong HK, Cho H, Kang KK, Park BS, Na KH, et al. Four-week Repeated Dose Toxicity Study of Recombinant Human Basic Fibroblast Growth Factor by Subcutaneous Administration in Rats. Toxicological Research. 1999;15. 6、 Dong HK, Cho H, Kang KK, Ahn BO, Kim WB. Acute Toxicity Study on Recombinant Human Basic Fibroblast Growth Factor in Rats and Dogs. Toxicological Research. 1999;15. 7、 Meduri A, Aragona P, Grenga PL, Roszkowska AM. Effect of basic fibroblast growth factor on corneal epithelial healing after photorefractive keratectomy. Journal of refractive surgery (Thorofare, NJ : 1995). 2012;28(3):220-3. Eras Z, Gokmen T, Erdeve O, Ozyurt BM, Saridas B, Dilmen U. Am J Perinatol. 2013 Nov;30(10):857-62. doi: 10.1055/s-0033-1333667. Epub 2013 Jan 28. 8、 Intravenous ibuprofen?for postoperative pain. Kroll PB. Pain Manag. 2012 Jan;2(1):47-54. doi: 10.2217/pmt.11.68. 9、 A multicenter, randomized, double-blind,   [更多]

內(nèi)容： 1、Crump M, et al. A Phase III Study of Enzastaurin in Patients with High-Risk Diffuse Large B Cell Lymphoma Following Response to Primary Treatment: The Prelude Trial. Blood 2013; 122:371 2、Prevalence of mucosal lesions in the stomach and duodenum due to chronic use of NSAID in patients with rheumatoid arthritis or osteoarthritis, and interim report on prevention by misoprostol of diclofenac associated lesions. J Rheumatol Suppl. 1991 Mar;28:11-4. 要求：上傳符合內(nèi)容的PDF格式，先到先得   [更多]